On 24 and 25 May, EU leaders met physically in Brussels to discuss the most pressing issues.

On 24 May leaders discussed the forced landing of a Ryanair flight in Minsk and subsequent arrest of anti-government activist and journalist Roman Protasevich. EU leaders invited Council to adopt further sanctions and necessary measures to ban overflight of EU airspace by Belarusian airlines and prevent access to EU airports of flights operated by such airlines. They also called on all EU-based carriers to avoid overflight of Belarus. Leaders also had the state of play of the coordination of the EU's response to COVID-19 on the agenda. They held a strategic debate on Russia and discussed the EU's relations with the UK, following the entry into force of the EU-UK trade and cooperation agreement on 1 May 2021.