The Prodi Commission was the European Commission in office between 1999 and 2004. The administration was led by former Italian Prime Minister Romano Prodi.
The commission took office on 16 September 1999 following the scandal and subsequent resignation of the Santer Commission which had damaged the reputation of the institution. The College consisted of 20 Commissioners which grew to 30 following the Enlargement of the European Union in 2004. It was the last commission to see two members allocated to the larger member states.